Fa'amatalaga Lautele
Matrix metallopeptidase 3 (faapuupuuina o le MMP3) e lauiloa foi o le stromelysin 1 ma le progelatinase.MMP3 o se sui o le matrix metalloproteinase (MMP) aiga o latou tagata o loʻo aʻafia i le malepelepe o le extracellular matrix i faiga masani o le physiological, e pei o le tuputupu aʻe o le tino, toe gaosia, toe faʻaleleia o le tino, ma faʻamaʻi faʻamaʻi e aofia ai le gasegase ma le metastasis.I le avea ai o se endopeptidase faʻalagolago i le zinc, MMP3 o loʻo faʻatinoina ana galuega faʻapitoa i le matrix extracellular.O lenei polotini e fa'aagaoioia e ni fa'ainitaneti tetele e lua: alpha2-macroglobulin ma fa'ainisinia o mea'ai o metalloproteases (TIMPs).MMP3 o loʻo i ai se sao tutotonu i le faʻaleagaina o ituaiga collagen II, III, IV, IX, ma X, proteoglycans, fibronectin, laminin, ma elastin.E le gata i lea, e mafai e le MMP3 ona fa'agaoioia isi MMP e pei o le MMP1, MMP7, ma le MMP9, e fa'atauaina ai le MMP3 i le toe fa'afouina o mea fa'afeso'ota'i.Le fa'atonutonuina o MMPs ua a'afia i le tele o fa'ama'i e aofia ai le gugu, ma'i ma'i tumau, encephalomyelitis, ma le kanesa.O mea fa'ainitaneti po'o fa'alenatura ole MMP e mafua ai le fa'asaina ole metastasis, ae o le fa'atulafonoina ole MMP na ta'ita'ia ai le fa'atupuina o le osofa'iga o sela o le kanesa.
Fautuaga paga | CLIA (Pu'e-Su'eina): 11G11-6 ~ 8A3-9 11G11-6 ~ 5B9-4 |
mama | >95%, fuafuaina e le SDS-PAGE |
Fausia Fa'amau | PBS, pH7.4. |
Teuina | Teuina i lalo o tulaga faʻamaʻi ile -20 ℃ i le -80 ℃ pe a maua. Fautuaina e fa'amama le polotini i ni vaega laiti mo le teuina lelei. |
Igoa Oloa | Pusi.Leai | Clone ID |
MMP-3 | AB0025-1 | 11G11-6 |
AB0025-2 | 8A3-9 | |
AB0025-3 | 5B9-4 |
Fa'aaliga: Bioantibody e mafai ona fa'avasega le aofa'i mo lou mana'oga.
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2. Hattori Y , Kida D , Kaneko A .Ole la'asaga masani ole matrix metalloproteinase-3 e mafai ona fa'aoga e va'ai ai le fa'amagaloga ile falema'i ma galuega fa'aletino masani i tagata mama'i e maua i le ma'i rūmatoid [J].Falema'i Rheumatology, 2018.