Fa'amatalaga Lautele
Sex hormone binding globulin (SHBG) o se glycoprotein e tusa ma le 80-100 kDa;o loʻo i ai se fesoʻotaʻiga maualuga mo 17 beta-hydroxysteroid hormones pei ole testosterone ma estradiol.SHBG
O le fa'atonuga i le plasma e fa'atulafonoina e, fa'atasi ai ma isi mea, paleni androgen/estrogen, hormones thyroid, inisalini ma mea'ai.O le porotini felauaiga sili ona taua mo estrogens ma androgens i le toto lautele.O le fa'atonuga o le SHBG ose mea taua tele e fa'atonutonu ai lo latou tufatufaina i le va o le polotini ma le sa'olotoga.Plasma SHBG concentrations e
afaina i le tele o faʻamaʻi eseese, tulaga maualuga o loʻo maua i le hyperthyroidism, hypogonadism, androgen insensitivity ma le ate cirrhosis i tane.O fa'amaulalo maualalo e maua ile myxoedema, hyperprolactinaemia ma fa'ama'i o le tele o gaioiga androgen.Fua o le SHBG e aoga i le iloiloga o faʻafitauli vaivai o le metabolism androgen ma mafai ai ona faʻamaonia na fafine e maua i le hirsutism e sili atu ona tali atu i le estrogen therapy.
Fautuaga paga | CLIA (Pu'e-Su'eina): 3E10-1 ~ 3A10-5 3A10-5 ~ 3D8-2 |
mama | >95%, fuafuaina e le SDS-PAGE |
Fausia Fa'amau | PBS, pH7.4. |
Teuina | Teuina i lalo o tulaga faʻamaʻi ile -20 ℃ i le -80 ℃ pe a maua. Fautuaina e fa'amama le polotini i ni vaega laiti mo le teuina lelei. |
Igoa Oloa | Pusi.Leai | Clone ID |
SHBG | AB0030-1 | 3A10-5 |
AB0030-2 | 3E10-1 | |
AB0030-3 | 3D8-2 |
Fa'aaliga: Bioantibody e mafai ona fa'avasega le aofa'i mo lou mana'oga.
1. Selby C. Sex hormone binding globulin: tupuaga, galuega ma le taua o le falema'i.Ann Clin Biochem 1990;27:532-541.
2. Pugeat M, Crave JC, Tourniare J, et al.Fa'amanino aoga ole fuaina o le globulin fa'afeusuaiga hormone.Horm Res 1996;45(3-5):148-155.