Anti-tagata CHI3L1 Antibody, Monoclonal tagata
Fa'amatalaga o oloa
Fa'amatalaga Lautele
Chitinase-3-pei o le polotini 1 (CHI3L1) o se glycoprotein fa'alilolilo fa'amaufa'atasi o lona fa'aaliga e feso'ota'i ma le femalaga'iga o maso lamolemole vascular.O le CHI3L1 o loʻo faʻaalia i tulaga maualuga i aganuʻu VSMC nodular postconfluent ma i tulaga maualalo i aganuʻu faʻateleina faʻateleina.O le CHI3L1 o se mea faʻasaina, chitin-binding lectin ma se sui o le glycosyl hydrolase family 18. I le faʻatusatusa i le tele o isi faʻailoga monocyto / macrophage, o lona faʻaaliga e le o iai i monocytes ma malosi faʻaosoina i taimi tuai o le eseesega o le macrophage tagata.Ole maualuga ole CHI3L1 e feso'ota'i ma fa'aletonu e fa'aalia ai le fa'ateleina ole suiga ole tino, e pei ole rheum atoid, gugu, osteoarthritis, scleroderma, ma le cirrhosis o le ate, ae e gaosia ile cartilage mai tagata foa'i tuai po'o tagata gasegase e maua i le osteoarthritis.O le CHI3L1 e le masani ona faʻaalia i totonu o le hippocampus o mataupu e maua i le schizophrenia ma e ono aʻafia i le tali feaveaʻi i le tele o mea tau le siosiomaga e lipotia mai e faʻateleina ai le lamatiaga o le schizophrenia.
Meatotino
| Fautuaga paga | CLIA (Pu'e-Su'eina): 2E4-2 ~ 1G11-14 13F3-1 ~ 1G11-14 |
| mama | >95%, fuafuaina e le SDS-PAGE |
| Fausia Fa'amau | PBS, pH7.4 |
| Teuina | Teuina i lalo o tulaga faʻamaʻi ile -20 ℃ i le -80 ℃ pe a maua. Mo le teuina umi, faamolemole aliquot ma teu.Aloese mai ta'amilosaga fa'aaisa ma liusua faifai pea. |
Iloiloga Faatusatusa
| Bioantibody | ma'i fa'ama'i fa'ama'i | Aofa'iga | |
| lelei | Le lelei | ||
| lelei | 46 | 3 | 49 |
| Le lelei | 4 | 97 | 101 |
| Aofa'iga | 50 | 100 | 150 |
| faasinoupu o iloiloga | maaleale | fa'apitoa | sa'o |
| 92% | 97% | 95% | |
Fa'amatalaga oka
| Igoa Oloa | Pusi.Leai | Clone ID |
| CHI3L1 | AB0031-1 | 1G11-14 |
| AB0031-2 | 2E4-2 | |
| AB0031-3 | 3A12-1 | |
| AB0031-4 | 13F3-1 |
Fa'aaliga: Bioantibody e mafai ona fa'avasega le aofa'i mo lou mana'oga.
Upusii
1.Kyrgios I , Galli-Tsinopoulou A , Stylianou C , et al.O le maualuga o le ta'amilosaga maualuga o le serum acute-phase protein YKL-40 (chitinase 3-like protein 1) o se fa'ailoga o le tino puta ma le inisalini tete'e i tamaiti a'o le'i fa'ataoto [J].Metabolism-clinical & Experimental, 2012, 61 (4): 562-568.
2.Yu-Huan M , Li-Ming T , Jian-Ying LI , et al.Iloiloga i luga o le faʻaogaina o le serum chitinase-3-like protein 1, alpha-fetoprotein ma ferritin detection i le suʻesuʻeina o le hepatocellular carcinoma [J].Vailaau Fa'ata'ita'i Puipuia, 2018.
