Anti-tagata GDF15 Antibody, Mouse Monoclonal
Fa'amatalaga o oloa
Fa'amatalaga Lautele
Growth-differentiation factor 15 (GDF15), lea e taʻua foi o le MIC-1, o se sui faalilolilo o le suiga o le tuputupu aʻe (TGF) -β superfamily, e avea o se mea fou e faʻatonutonu ai le hypertrophic i le fatu.GDF-15 / GDF15 e le o faʻaalia i le fatu masani o tagata matutua ae faʻaosoina i le tali atu i tulaga e faʻateleina ai le hypertrophy ma le faʻalauteleina o le cardiomyopathy ma e faʻaalia maualuga i le ate.GDF-15 / GDF15 o loʻo i ai se sao i le faʻatonutonuina o auala inflammatory ma apoptotic i aano manuʻa ma i taimi o faʻamaʻi.GDF-15 / GDF15 o loʻo tuʻufaʻatasia e pei o molelaʻau muamua o loʻo faʻagasolo i se nofoaga cleavage dibasic e faʻasaʻo ai vaega C-terminal o loʻo i ai se uiga faʻapitoa o cysteines faʻasaoina e 7 i le polotini matua.GDF-15 / GDF15 overexpression e mafua mai i le faʻalauteleina o le erythroid vaega e fesoasoani i le mamafa o le uʻamea i faʻamaʻi talasemia e ala i le taofia o le faʻaaliga o le hepcidin.
Meatotino
| Fautuaga paga | CLIA (Pu'e-Su'eina): 23F1-5 ~ 6C1-9 23F1-5 ~ 3A2-1 |
| mama | >95%, fuafuaina e le SDS-PAGE |
| Fausia Fa'amau | PBS, pH7.4. |
| Teuina | Teuina i lalo o tulaga faʻamaʻi ile -20 ℃ i le -80 ℃ pe a maua. Fautuaina e fa'amama le polotini i ni vaega laiti mo le teuina lelei. |
Faatusatusaga Faatauva
Fa'amatalaga oka
| Igoa Oloa | Pusi.Leai | Clone ID |
| GDP-15 | AB0038-1 | 3A2-1 |
| AB0038-2 | 23F1-5 | |
| AB0038-3 | 6C1-9 | |
| AB0038-4 | 4D5-8 |
Fa'aaliga: Bioantibody e mafai ona fa'avasega le aofa'i mo lou mana'oga.
Upusii
1.Wollert KC , Kempf T , Peter T , et al.Tulaga Taua o le Tuputupu-Fa'aeseesega Factor-15 i ma'i e le o ST-Elevation Acute Coronary Syndrome [J].Fa'asalalau, 2007, 115(8):962-971.
2.Kempf T , Haehling SV , Peter T , et al.Fa'atonuga fa'apitoa o le fa'avasegaina o le tuputupu a'e-15 i tagata mama'i e fa'aletonu le fatu.[J].Tusitala o le American College of Cardiology, 2007, 50(11):1054-1060.
