Anti-tagata TIMP1 Antibody, Mouse Monoclonal
Fa'amatalaga o oloa
Fa'amatalaga Lautele
TIMP metallopeptidase inhibitor 1, e lauiloa foi o le TIMP-1/TIMP1, Collagenase inhibitor 16C8 fibroblast Erythroid-potentiating activity, TPA-S1TPA-induced protein Tissue inhibitors of metalloproteinases 1, o se faʻalavelave faʻanatura o le matrix metalloproteinases (MMPs), o se vaega o peptidases. aafia i le faaleagaina o le matrix extracellular.TIMP-1/TIMP1 o lo'o maua i le fetal ma tagata matutua.Ole maualuga maualuga e maua ile ponaivi, mama, ovary ma le matua.Fa'alavelave fa'atasi ma metalloproteinases ma e le mafai ona toe fa'afo'isia i latou e ala i le fusifusia i lo latou fa'aupuga zinc catalytic.TIMP-1 / TIMP1 faʻasalalau erythropoiesis in vitro;ae, e le pei o le IL-3, o ituaiga-faʻapitoa, faʻaosofia le tuputupu aʻe ma le eseesega o naʻo tagata ma murine erythroid progenitors.I le faʻaopoopoga i lona faʻalavelave faʻasaga i le tele o MMPs ua iloa, o le polotini e mafai ona faʻalauteleina le faʻalauteleina o sela i le tele o ituaiga sela, ma e mafai foi ona i ai se galuega anti-apoptotic.O le fa'aliliuga o lenei ga'o e fa'aliliuina ai le porotini e matua fa'ailoaina i le tali atu i le tele o cytokines ma hormones.E le gata i lea, o le faʻamatalaga mai nisi ae le o mea uma o le X chromosomes e taʻu mai ai o lenei gene inactivation o le polymorphic i fafine tagata.O lo'o i totonu o le intron 6 o le gene synapsin I lea gene encoding ma o lo'o tusia i le isi itu.Fa'alavelave fa'atasi ma metalloproteinases ma e le mafai ona toe fa'afo'isia i latou e ala i le fusifusia i lo latou fa'aupuga zinc catalytic.TIMP-1/TIMP1 ua lauiloa e galue i le MMP-1, MMP-2, MMP-3, MMP-7, MMP-8, MMP-9, MMP-10, MMP-11, MMP-12, MMP-13 ma MMP-16.
Meatotino
| Fautuaga paga | CLIA (Pu'e-Su'eina): 1D5-5 ~ 3G11-6 1D12-2 ~ 1G3-7 |
| mama | >95% e pei ona fuafuaina e le SDS-PAGE. |
| Fausia Fa'amau | PBS, pH7.4. |
| Teuina | Teuina i lalo o tulaga faʻamaʻi ile -20 ℃ i le -80 ℃ pe a maua. Fautuaina e fa'amama le polotini i ni vaega laiti mo le teuina lelei. |
Faatusatusaga Faatauva
Fa'amatalaga oka
| Igoa Oloa | Pusi.Leai | Clone ID |
| TIMP1 | AB0034-1 | 1D5-5 |
| AB0034-2 | 1D12-2 | |
| AB0034-3 | 1G3-7 | |
| AB0034-4 | 3G11-6 |
Fa'aaliga: Bioantibody e mafai ona fa'avasega le aofa'i mo lou mana'oga.
Upusii
1.Barylski M, Kowalczyk E, Szadkowska I, et al.[Issue inhibitor of metalloproteinases[J].Polski Merkuriusz Lekarski Organ Polskiego Towarzystwa Lekarskiego, 2011, 30(178):246-8.
2. Hayakawa T , Yamashita K , Tanzawa K , et al.O le fa'atupuina o le fa'atupuina o le gaioioiga a le mea e taofia ai le tino o metalloproteinases-1 (TIMP-1) mo le tele o sela O se mea fou e mafai ona tuputupu aʻe i le toto [J].Tusi FEBS, 1992, 298.
3.Haider DG, Karin S, Gerhard P, et al.Serum retinol-binding protein 4 e faʻaitiitia pe a uma le paʻu o le mamafa i mataupu e sili ona lapopoa.[J].Journal of Clinical Endocrinology & Metabolism(3):1168-71.
