Fa'amatalaga Lautele
S100B o se polotini e fusifusia ai le calcium, lea e natia mai i astrocytes.O se polotini cytosolic dimeric dimeric (21 kDa) e aofia ai filifili ββ poʻo αβ.S100B o loʻo aʻafia i le tele o gaioiga faʻatonutonu intracellular ma extracellular.
I le sefulu tausaga talu ai, S100B ua tulaʻi mai o se sui faʻataʻitaʻiga o le biomarker o le toto-faiʻai (BBB) faʻaleagaina ma le CNS manua.Ole maualuga ole maualuga ole S100B e atagia saʻo ai le iai o tulaga o le neuropathological e aofia ai manuʻa ulu ma faʻamaʻi neurodegenerative.Ole maualuga ole S100B e fa'amoemoeina e le aofia ai fa'ama'i CNS.Serum S100B ua lipotia mai foi o se faailoga aoga mo le vave iloa o metastases o le melanoma ma le cerebral complications mai manua o le ulu, taotoga o le fatu, ma le maʻi stroke.
Fautuaga paga | CLIA (Pu'e-Su'eina): 5H2-3 ~ 22G7-5 22G7-5 ~ 5H2-3 |
mama | >95% e pei ona fuafuaina e le SDS-PAGE. |
Fausia Fa'amau | 20 mM PB, 150 mM NaCl, 0.1% Proclin 300,pH7.4 |
Teuina | Teuina i lalo o tulaga faʻamaʻi ile -20 ℃ i le -80 ℃ pe a maua. Fautuaina e fa'amama le polotini i ni vaega laiti mo le teuina lelei. |
Igoa Oloa | Pusi.Leai | Clone ID |
s100 β | AB0061-1 | 5H2-3 |
AB0061-2 | 22G7-5 | |
AB0061-3 | 21A6-1 |
Fa'aaliga: Bioantibody e mafai ona fa'avasega le aofa'i mo lou mana'oga.
1. Ostendorp T , Leclerc E , Galichet A , et al.Malamalamaga faʻavae ma faʻatinoga ile faʻagaioiina o le RAGE e le multimeric S100B[J].Le EMBO Journal, 2007, 26(16):3868-3878.
2. R, D, Rothoerl, et al.Ole maualuga ole S100B ole toto mo tagata gasegase e leai ni manu'a ulu.[J].Neurosurgery, 2001.